Science resources



A list of scientific publications produced by researchers at the Anticancer Fund, or acknowledging our support.


Summary results as of last build on: 02/10/24NumberPercentage
Total number of publications112
Authored by ACF9584.82%
Acknowledges ACF support1715.18%
Full text available (open access)9282.14%


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Database build date: 02/10/24

Number of publications in database: 112 (Filter not active)



Authors ACF Contribution Title Type Journal/Conference Pub Date External Link ACF Link Full Text Key Words
Julie De Smedt, Sofie Van Kelst, Laudine Janssen, Vivien Marasigan, Veerle Boecxstaens, Kris Bogaerts, Ann Belmans, Dirk Vanderschueren, Katleen Vandenberghe, Oliver Bechter, Claudia Aura, Diether Lambrechts, Tinne Strobbe, Gabriella Emri, Arjen Nikkels, Marjan Garmyn Acknowledged High-dose vitamin D supplementation does not improve outcome in a cutaneous melanoma population: results of a randomized double-blind placebo-controlled study (ViDMe trial) Journal Article British Journal of Dermatology 2024-06-24 Link Link N Vitamin D3, melanoma, clinical trial
G. Kuijten, J. Hermans, L. Vandeborne, K. Rombauts, G. Buyens, M. Bollue, P. Deroost, R. Janssens, I. Huys Author Impact of the free information service My Cancer Navigator according to patients and their relatives: An online survey Journal Article Annals of Oncology 2024-09-16 Link Link Y Online survey, patient experience, My Cancer Navigator
Darrell Green, Roelof van Ewijk, Elisa Tirtei, Dimosthenis Andreou, Fredrik Baecklund, Daniel Baumhoer, Stefan S Bielack, Rajesh Botchu, Kjetil Boye, Bernadette Brennan, Michael Capra, Lucia Cottone, Uta Dirksen, Franca Fagioli, Natalia Fernandez, Adrienne M Flanagan, Marco Gambarotti, Nathalie Gaspar, Hans Gelderblom, Craig Gerrand, Anne Gomez-Mascard, Jendrik Hardes, Stefanie Hecker-Nolting, Edita Kabickova, Leo Kager, Jukka Kanerva, Lennart A Kester, Marieke L Kuijjer, Valérie Laurence, Cyril Lervat, Antonin Marchais, Perrine Marec-Berard, Cristina Mendes, Johannes H M Merks, Benjamin Ory, Emanuela Palmerini, Pan Pantziarka, Evgenia Papakonstantinou, Sophie Piperno-Neumann, Anna Raciborska, Elizabeth A Roundhill, Vilma Rutkauskaite, Akmal Safwat, Katia Scotlandi, Eric L Staals, Sandra J Strauss, Didier Surdez, Gwen M L Sys, Marie-Dominique Tabone, Maud Toulmonde, Claudia Valverde, Michiel A J van de Sande, Klaus Woertler, Quentin Campbell-Hewson, Martin G McCabe, Michaela Nathrath Author Biological sample collection to advance research and treatment: a Fight Osteosarcoma Through European Research (FOSTER) and Euro Ewing Consortium (EEC) statement Journal Article Clinical Cancer Research 2024-06-13 Link No link Y Sample collection, bone sarcomas, consensus statement, patient advocacy
Silvia Stacchiotti, Gauthier Bouche, Ralf Herold, Pan Pantziarka, Kathrin Schuster, Roger Wilson, Francesco Pignatti, Bernd Kasper Author How to develop new systemic treatments in ultra-rare cancers with high unmet needs? The case of alveolar soft-part sarcoma Journal Article European Journal of Cancer 2024-03-11 Link No link N Rare cancers, clinical trials, policy, methodology
Denise Robinson, Hugh Leonard, Giacomo Giulio Baldi, William D Tap, Robin L Jones, Silvia Stacchiotti, Pan Pantziarka Author The patient perspective on sirolimus for epithelioid hemangioendothelioma (EHE): results of a community survey highlighting the importance of equitable access to treatments Journal Article Frontiers in Oncology 2024-02-26 Link No link Y Sirolimus, EHE, drug repurposing, patient advocacy
Miriam Dixon-Zegeye, Rachel Shaw, Linda Collins, Kendra Perez-Smith, Alexander Ooms, Maggie Qiao, Pan Pantziarka, Louise Izatt, Marc Tischkowitz, Rachel E Harrison, Angela George, Emma R Woodward, Simon Lord, Lara Hawkes, D Gareth Evans, James Franklin, Helen Hanson, Sarah P Blagden Author Cancer Precision-Prevention trial of Metformin in adults with Li Fraumeni syndrome (MILI) undergoing yearly MRI surveillance: a randomised controlled trial protocol Journal Article Trials 2024-02-03 Link No link Y Li Fraumeni Syndrome, drug repurposing, clinical trial, cancer prevention
Christelle Bouchart, Julie Navez, Ivan Borbath, Karen Geboes, Timon Vandamme, Jean Closset , Luigi Moretti, Pieter Demetter, Marianne Paesmans, Jean-Luc Van Laethem Acknowledged Preoperative treatment with mFOLFIRINOX or Gemcitabine/Nab-paclitaxel +/- isotoxic high-dose stereotactic body Radiation Therapy (iHD-SBRT) for borderline resectable pancreatic adenocarcinoma (the STEREOPAC trial): study protocol for a randomised comparative multicenter phase II trial Journal Article BMC Cancer 2023-09-21 Link No link Y Pancreatic cancer, Radiotherapy, Clinical trial
Ian F. Tannock, Gauthier Bouche, Daniel A. Goldstein, Yasushi Goto, Allen S. Lichter, Kumar Prabhash, Priya Ranganathan, Leonard B. Saltz, Gabe S. Sonke, Garth W. Strohbehn, Roger von Moos, Mark J. Ratain Author Patient-centred, self-funding dose optimisation trials as a route to reduce toxicity, lower cost and improve access to cancer therapy Journal Article Annals of Oncology 2023-05-22 Link No link N Clinical trials, Policy, Methodology
Pan Pantziarka, Ian Roberts, Patricia Vandamme, Lydie Meheus, Gauthier Bouche Author Drug evidence watch: a process to the benefit of public health Journal Article The Lancet 2023-04-12 Link No link Y Drug development, drug repurposing, medical regulation, health policy
Pierre Leblond, Emmanuelle Tresch-Bruneel, Alicia Probst, Nadège Néant, Caroline Solas, Arthur Sterin, Thomas Boulanger, Isabelle Aerts, Cécile Faure-Conter, Anne-Isabelle Bertozzi, Pascal Chastagner, Natacha Entz-Werlé, Emilie De Carli, Marie-Cécile Le Deley, Gauthier Bouche, Nicolas André Author Phase I study of a combination of fluvastatin and celecoxib in 2 children with relapsing/refractory low-grade or high-grade gli-3 oma (FLUVABREX) Journal Article Cancers 2023-03-28 Link No link N Clinical trial, drug repurposing, pediatric cancer
Nicolas André, Guy Buyens, Eric Bouffet, David Walker, Matthew D Dun Author Access to new drugs in paediatric oncology: can we learn from the ongoing ONC201 saga? Journal Article Lancet Oncology 2023-02-14 Link No link N Drug development, pediatric oncology, ONC201, DIPG/DMG
Elizabeth Ann Roundhill, Pan Pantziarka, Danielle E. Liddle, Lucy A. Shaw, Ghadeer Albadrani and Susan Ann Burchill Author Exploiting the Stemness and Chemoresistance Transcriptome of Ewing Sarcoma to Identify Candidate Therapeutic Targets and Drug‐Repurposing Candidates Journal Article Cancers 2023-01-26 Link No link Y Ewing sarcoma, stemness, pluripotency, CD133, multidrug resistance, ABCG1, POU5F1/CT-4, drug repurposing
Guy Buyens, Michael van Balken, Kathy Oliver, Richard Price, Lawler M, Nicolò Matteo Luca Battisti, Hein Van Poppel, Enea Venegonie Author Cancer literacy - Informing patients and implementing shared decision making Journal Article Journal of Cancer Policy 2022-12-01 Link No link N Health literacy, shared decision making, patient support, patient education
Gauthier Bouche, Ruth Langley, Hannah Rush, Mahesh Parmar, Duncan C. Gilbert Author Testing alternative schedules of adjuvant immune checkpoint blockers – The need for well-designed clinical trials Journal Article European Journal of Cancer 2022-11-22 Link No link N Clinical trial design, methodology
Elisabeth De Waele, Joy Demol, Koen Huysentruyt, Geir Bjørklund, Ronald Buyl, Alessandro Laviano and Joeri J. Pen Acknowledged Nutrition Therapy Promotes Overall Survival in Cachectic Cancer Patients through a New Proposed Chemical-Physical Pathway: The TiCaCONCO Trial (A Randomized Controlled Single-Blinded Trial) Journal Article Appetite 2022-11-01 Link No link N Cancer cachexia, nutrition, randomised trial, TiCaCONCO trial
Hendrik Van Poppel, MD, PhD; Nicolo Matteo Luca Battisti, MD; Mark Lawler, PhD; Teodora Kolarova, MA; Jacqueline Daly, BSc; Katie Rizvi, BSc; Robert Greene, BSc; Guy Buyens, MD; Kathy Oliver, BSc; Richard Price, BA; Nela Osmanovic, MSc; Enea Venegoni, BSc Author European Cancer Organisation’s Inequalities Network: Putting Cancer Inequalities on the European Policy Map Journal Article JCO Global Oncology 2022-10-17 Link No link Y Health inequalities, cancer, health policy, European Cancer Organisation
Rica Capistrano I, Sonz Paul, Ingrid Boere, Pan Pantziarka, Supriya Chopra, Remi A Nout and Gauthier Bouche Author Drug repurposing as a potential source of innovative therapies in cervical cancer Journal Article Intl Journal of Gynecological Cancer 2022-09-22 Link Link Y Cervical cancer, drug repurposing
Charlotte Ouimet,Gauthier Bouche, Jonathan Kimmelman Author Diminishing clinical impact for post-approval cancer clinical trials: A retrospective cohort study Journal Article PLoS ONE 2022-09-12 Link No link Y Drug approvals, drug repurposing, cancer policy, regulatory science
Emiel A. De Jaeghere, Sandra Tuyaerts, An M. T. Van Nufel, Ann Belmans, Kris Bogaerts, Regina Baiden‑Amissah, Lien Lippens, Peter Vuylsteke, Stéphanie Henry, Xuan Bich Trinh, Peter A. van Dam, Sandrine Aspeslagh, Alex De Caluwé, Eline Naert, Diether Lambrechts, An Hendrix, Olivier De Wever, Koen K. Van de Vijver, Frédéric Amant, Katrien Vandecasteele, Hannelore G. Denys Author Pembrolizumab, radiotherapy, and an immunomodulatory five‑drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma: Results of the phase II PRIMMO study Journal Article Cancer Immunology, Immunotherapy 2022-08-12 Link Link Y Computational model, mathematical oncology, evolutionary algorithm, machine learning
Pan Pantziarka, Lina Ghibelli, Albrecht Reichle Author The Effect of Over-Feeding in a Computational Model of Tumour Growth Journal Article Cancer, Complexity, Computation (book) 2022-08-12 Link No link N Computational model, mathematical oncology, evolutionary algorithm, machine learning
Maud Toulmonde, Perrine Marec-Berard, Cyril Lervat, Coralie Cantarel, Emilie Toulza, Sabrina Sellan-Albert, Sophie Cousin, Kevin Bourcier, Mariella Spalato-Ceruso, Raul Perret, Simone Mathoulin-Pelissier, Jean-Yves Blay, Nicolas Penel, Carine Bellera and Antoine Italiano Acknowledged METZOLIMOS Metronomic Cyclophosphamide (CP) and Methotrexate (MTX) combined with Zoledronic Acid (ZA) and Sirolimus (SIR) in patients with advanced Solid Tumor with bone metastasis and advanced pretreated Osteosarcoma (OSS) A Phase Ib Study Poster ASCO 2022 2022-06-09 Link Link Y Osteosarcoma, drug repurposing, clinical trial results, ASCO
Pamela M. J. McLaughlin, Maximilian Klar, Tibor A. Zwimpfer, Gilles Dutilh, Marcus Vetter, Christian Marth, Andreas du Bois, Carmen Schade‑Brittinger, Alexander Reuss, Claudine Bommer, Christian Kurzeder and Viola Heinzelmann‑Schwarz Acknowledged Maintenance Therapy with Aromatase Inhibitor in epithelial Ovarian Cancer (MATAO): study protocol of a randomized double‑blinded placebo‑controlled multi‑center phase III Trial Journal Article BMC Cancer 2022-05-06 Link No link Y Ovarian cancer, clinical trial protocol, letrozole
Julie De Smedt, Sofie Van Kelst, Laudine Janssen, Vivien Marasigan, Veerle Boecxstaens, Marguerite Stas, Dirk Vanderschueren, Ipek Guler, Kris Bogaerts, Katleen Vandenberghe, Olivier Bechter, Jaak Billen, Arjen Nikkels, Tine Strobbe, Gabriella Emri, Diether Lambrechts, Marjan Garmyn Acknowledged Determinants of 25-hydroxyvitamin D Status in a Cutaneous Melanoma Population Journal Article Advances in Dermatology and Venereology 2022-03-21 Link Link Y melanoma; vitamin D; body mass index
Gauthier Bouche, Lydie Meheus Author Ensuring completeness and timeliness of cancer treatment guidelines Journal Article Nature Reviews Clinical Oncology 2022-05-20 Link Link N Cancer treatment, treatment guidelines, patient access, drug repurposing
Pan Pantziarka, Sarah Blagden Author Inhibiting the Priming for Cancer in Li-Fraumeni Syndrome Journal Article Cancers 2022-03-23 Link No link Y Li Fraumeni Syndrome, precancerous niche, drug repurposing
Charlotte Asker-Hagelberg, Tomas Boran, Christelle Bouygues, Sini Marika Eskola, Laszlo Helmle, César Hernández, François Houÿez, Helen Lee, Dimitra D. Lingri, Laurent Louette, Lydie Meheus, Wim Penninckx and Beata Stepniewska Author Repurposing of Medicines in the EU: Launch of a Pilot Framework Journal Article Frontiers in Medicine 2022-01-10 Link No link Y Drug repurposing, cancer policy, regulatory science
Pan Pantziarka, Liese Vandeborne and Gauthier Bouche Author A Database of Drug Repurposing Clinical Trials in Oncology Journal Article Frontiers in Pharmacology 2021-11-10 Link No link Y Drug repurposing, Clinical trials, database
P Leblond, A Probst, N Entz-Werlé, AS Defachelles, I Aerts, E Bogart, AM Bimbai, MC Le Deley, N André Acknowledged METRO-PD1: A Phase I Feasibility Study Evaluating Anti-PD1 (NIVOLUMAB) In Combination With Metronomic Chemotherapy In Children And Teenagers With Refractory/Relapsing Solid Tumors Or Lymphoma Poster SIOP 2021 2021-10-21 No link Link Y Clinical trial, drug repurposing, checkpoint inhibitors, pediatric cancer
Rica Capistrano, Sonz Paul, Ingrid A. Boere, Pan Pantziarka, Supriya Chopra, Remi A. Nout, Gauthier Bouche Author Drug repurposing as a source of innovative therapies in cervical cancer Poster ESGO 2021 2021-10-23 No link Link Y Cervical cancer, drug repurposing
Sergio Crispino, Klara Rombauts, Pan Pantziarka, Gauthier Bouche Author Drug repurposing candidates in the treatment of brain metastases Poster Brain Metastases Research and Emerging Therapy Conference 2021-09-29 No link Link Y Brain metastases, drug repurposing, new treatment options
Bishal Gyawali, Richard Sullivan, Christopher M Booth Acknowledged Cancer groundshot: going global before going to the moon Journal Article Lancet Oncology 2018-03-19 Link Link Y Cancer policy, global health, patient benefit
Marc-Eric Halatsch, Richard E. Kast, Georg Karpel-Massler, Benjamin Mayer, Oliver Zolk, Bernd Schmitz, Angelika Scheuerle, Ludwig Maier, Lars Bullinger, Regine Mayer-Steinacker, Carl Schmidt, Katharina Zeiler, Ziad Elshaer, Patricia Panther, Birgit Schmelzle, Anke Hallmen, Annika Dwucet, Markus D. Siegelin, Mike-Andrew Westhoff, Kristine Beckers, Gauthier Bouche, and Tim Heiland Author A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3 Journal Article Neuro-Oncology Advances 2021-08-07 Link Link Y Glioblastoma Multiforme, GBM, drug repurposing, CUSP9v3, clinical trial
Sandrina Martens, Katarina Coolens, Mathias Van Bulck, Tatjana Arsenijevic, Joan Casamitjana, Angel Fernandez Ruiz, Abdessamad El Kaoutari, Jaime Martinez de Villareal, Hediel Madhloum, Farzad Esni, Yves Heremans, Gunter Leuckx, Harry Heimberg, Luc Bouwens, Patrick Jacquemin, Diedert Luc De Paep, Peter in't Veld, Nicky D'Haene, Christelle Bouchart, Nelson Dusetti, Jean-Luc Van Laethem, Wim Waelput, Pierre Lefesvre, Francisco X Real, Meritxell Rovira, Ilse Rooman Author Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease Journal Article Gut 2021-07-30 Link Link Y Pancreatic cancer, basic science, animal models, basal-like molecular subtype
Nathalie C Støer, Gauthier Bouche, Pan Pantziarka, Erica K Sloan, Bettina K Andreassen, Edoardo Botteri Author Use of non-cancer drugs and survival among patients with pancreatic adenocarcinoma: a nationwide registry-based study in Norway Journal Article Acta Oncologica 2021-08-02 Link Link N Retrospective study, drug repurposing, statins, pancreatic cancer
Gauthier Bouche, Eric Bouffet, Liese Vandeborne, Rica Capistrano, Nicolas André Author Diffuse intrinsic pontine glioma: a clinic in Mexico, social media, and unpublishable data Journal Article Lancet Oncology 2021-05-22 Link No link Y Pediatric cancer, ethics, perspective, diffuse intrinsic pontine glioma, Mexican clinics
Liese Vandeborne, Pan Pantziarka, An M. T. Van Nuffel and Gauthier Bouche Author Repurposing Infectious Diseases Vaccines Against Cancer Journal Article Frontiers in Oncology 2021-05-13 Link Link Y Infectious diseases vaccines, drug repurposing, immunotherapy
Ciska Verbaanderd, Ilse Rooman, Isabelle Huys Author Exploring new uses for existing drugs: Innovative mechanisms to fund independent clinical research Journal Article Trials 2021-05-04 Link Link Y Drug repurposing, clinical trials, health economics, trialfunding
Elena Vagia, Massimo Cristofanilli Acknowledged New Treatment Strategies for the Inflammatory Breast Cancer Journal Article Current Treatment Options in Oncology 2021-04-24 Link No link Y Inflammatory breast cancer, clinical trial design, review
John A Hickman, Ian F Tannock, Lydie Meheus, Lisa Hutchinson Author The European Union and personalised cancer medicine Journal Article European Journal of Cancer 2021-04-20 Link No link N Personalised medicine, health policy, clinical trial design
Daniel Heudoble, Christian Schulz, Jürgen R. Fischer, Peter Staib, Thomas Wehler, Thomas Südhoff, Thomas Schichtl, Jochen Wilke, Joachim Hahn, Florian Lüke, Martin Vogelhuber, Sebastian Klobuch, Tobias Pukrop, Wolfgang Herr, Swantje Held, Kristine Beckers, Gauthier Bouche, Albrecht Reichle Author A Randomized Phase II Trial Comparing the Efficacy and Safety of Pioglitazone, Clarithromycin and Metronomic Low-Dose Chemotherapy with Single-Agent Nivolumab Therapy in Patients with Advanced Non-small Cell Lung Cancer Treated in Second or Further Line (ModuLung) Journal Article Frontiers in Pharmacology 2021-03-16 Link Link Y Anakoinosis, clinical trial, non-small cell lung cancer
Pan Pantziarka, Rica Capistrano I, Arno De Potter, Liese Vandeborne and Gauthier Bouche Author An Open Access Database of Licensed Cancer Drugs Journal Article Frontiers in Pharmacology 2021-03-11 Link Link Y Repurposing, cancer drugs, pharmacology
Rachel Abudu, BS, MPH; Gauthier Bouche, MPH, MD; Karima Bourougaa, PhD; Lynne Davies, PhD; Kalina Duncan, BS, MPH; Carla Estaquio, PhD; Anna Diaz Font, PhD; Marc S. Hurlbert, PhD; Paul Jackson, PhD; Linda Kroeskop-Bossenbroek, PhD; Ian Lewis, PhD; Giota Mitrou, PhD; Abdul Mutabbir, BSc; Christopher A. Pettigrew, PhD; Lynn Turner, PhD; Annemarie Weerman, PhD; and Kari Wojtanik, PhD Author Trends in International Cancer Research Investment 2006-2018 Journal Article JCO Global Oncology 2021-03-10 Link Link Y Clinical trial funding, research trends, international comparisons
Christoffer Gebhardt, Sonja C S Simon, Rebekka Weber, Mirko Gries, Dong Hun Mun, Raphael Reinhard, Tim Holland-Letz, Viktor Umansky, Jochen Utikal Acknowledged Potential therapeutic effect of low-dose paclitaxel in melanoma patients resistant to immune checkpoint blockade: A pilot study Journal Article Cellular Immunology 2020-12-28 Link Link N Metronomic chemotherapy, melanoma, clinical trial, immuno-modulation
Gauthier Bouche, Craig Gedye, Lydie Meheus, Pan Pantziarka Author Drug repurposing in oncology Journal Article Lancet Oncology 2020-12-01 Link No link Y Correspondence, drug repurposing
Sergio Crispino, Pan Pantziarka, Lydie Meheus, Gauthier Bouche Author Finding existing drugs potentially active against BRCA mutated breast cancers: a literature based approach Poster EBCC-12 2020-10-01 Link Link Y Breast cancer, drug repurposing, literature search
Felix J Hüttner, Ilse Rooman, Gauthier Bouche, Phillip Knebel, Johannes Hüsing, André L Mihaljevic, Thilo Hackert, Oliver Strobel, Markus W Büchler, Markus K Diener Author Pancreatic resection with perioperative drug repurposing of propranolol and etodolac: trial protocol of the phase-II randomised placebo controlled PROSPER trial Journal Article BMJ Open 2020-09-30 Link Link Y pancreatic cancer, trial protocol, drug repurposing, propranolol, etodolac, PROSPER
Benson Chellakkan Selvanesan, Kiran Meena, Amanda Beck, Lydie Meheus, Olaya Lara, Ilse Rooman, Claudia Gravekamp Author Nicotinamide combined with gemcitabine is an immunomodulatory therapy that restrains pancreatic cancer in mice Journal Article Journal for Immunotherapy for Cancer 2020-09-29 Link Link Y Pancreatic cancer, nicotinamide, immunomodulatory therapy, drug repurposing, preclinical
Ciska Verbaanderd Author ReDIReCT - Repurposing of Drugs: Innovative Revision of Cancer Treatment Thesis 2020-09-24 No link Link Y drug repositioning, drug repurposing, off-label use, oncology, policy recommendations, regulatory framework, investigator-initiated studies, research funding, off-patent medicines
Heinhuis KM, IJzerman NS, Koenen AM, et al. Acknowledged PropAngio study protocol: a neoadjuvant trial on the efficacy of propranolol monotherapy in cutaneous angiosarcoma—a proof of principle study Journal Article BMJ Open 2020-09-18 Link Link Y Angiosarcoma, drug repurposing, study protocol, trial protocol, PropAngio
Rita Ahmed, Isaac Crespo, Sandra Tuyaerts, Amel Bekkar, Michele Graciotti, Ioannis Xenarios, Lana E. Kandalaft Acknowledged Predicting combinations of immunomodulators to enhance dendritic cell-based vaccination based on a hybrid experimental and computational platform. Journal Article Computational and Structural Biotechnology Journal 2020-08-08 Link Link Y Dendritic cell vaccines, immunomodulatory therapy
Andrea Spini, Sandra Donnini, Pan Pantziarka, Sergio Crispino, Marina Ziche Author Repurposing of drugs for triple negative breast cancer: an overview Journal Article Ecancermedicalscience 2020-07-13 Link Link Y Triple negative breast cancer, drug repurposing
Els Verdegaal, Monique K van der Kooij, Marten Visser, Caroline van der Minne, Linda de Bruin, Pauline Meij, Anton Terwisscha van Scheltinga, Marij J Welters, Saskia Santegoets, Noel de Miranda, Inge Roozen, Gerrit Jan Liefers, Ellen Kapiteijn and Sjoerd H van der Burg Acknowledged Low-dose interferon-alpha preconditioning and adoptive cell therapy in patients with metastatic melanoma refractory to standard (immune) therapies: a phase I/II study Journal Article Journal for ImmunoTherapy of Cancer 2020-04-01 Link Link Y metastatic melanoma, interferon-alpha, adoptive cell therapy, trial results
Christina Friese, Katja Harbst, Troels Holz Borch, Marie Christine Wulff Westergaard, Magnus Pedersen, Anders Kverneland, Göran Jönsson, Marco Donia, Inge Marie Svane, Özcan Met Acknowledged CTLA-4 blockade boosts the expansion of tumor-reactive CD8+ tumor-infiltrating lymphocytes in ovarian cancer Journal Article Scientific Reports 2020-03-03 Link Link Y recurrent ovarian cancer, Immune therapy, preclinical
Bishal Gyawali, Gauthier Bouche, Nigel Crisp and Nicolas André Author Challenges and opportunities for cancer clinical trials in low- and middle-income countries Journal Article Nature Cancer 2020-02-17 Link Link Y cancer, trial development, low- and middle-income countries
Ciska Verbaanderd, Ilse Rooman, Lydie Meheus, Isabelle Huys Author On-Label or Off-Label? Overcoming Regulatory and Financial Barriers to Bring Repurposed Medicines to Cancer Patients Journal Article Frontiers in Pharmacology 2020-01-31 Link Link Y Drug repurposing, regulatory and financial barriers
Pan Pantziarka, Ciska Verbaanderd, Isabelle Huys, Gauthier Bouche, Lydie Meheus Author Repurposing drugs in oncology: From candidate selection to clinical adoption Journal Article Seminars in Cancer Biology 2020-01-23 Link No link Y Review, drug repurposing
Bart J.T. Reymen, Marike W. van Gisbergen, Aniek J.G. Even, Catharina M.L. Zegers, Marco Das, Erik Vegt, Joachim E. Wildberger, Felix M. Mottaghy, Ala Yaromina, Ludwig J. Dubois, Wouter van Elmpt, Dirk De Ruysscher, Philippe Lambin Acknowledged Nitroglycerin as a radiosensitizer in non-small cell lung cancer: Results of a prospective imaging-based phase II trial Journal Article Clinical and Translational Radiation Oncology 2019-12-13 Link Link Y non-small cell lung cancer, trial results, nitroglycerin, drug repurposing
Pan Pantziarka, Ciska Verbaanderd, Lydie Meheus Author Biased by design? Clinical trials and patient benefit in oncology Journal Article Future Medicine 2019-12-11 Link Link Y clinical trials, bias
Daniel Heudobler, Sebastian Klobuch, Florian Lüke, Joachim Hahn, Matthias Grube, Stephan Kremers, Thomas Südhoff, Jörg Westermann, Marie Luise Hütter-Krönke, Peter Paschka, Gauthier Bouche, Hartmut Döhner, Wolfgang Herr, Simone Thomas, Albrecht Reichle Author Low-dose azacytidine, pioglitazone and retinoic acid in ≥ 60 years patients with acute myeloid leukaemia refractory to chemotherapy (AML-ViVA) Poster ASH 2019 2019-12-09 No link Link Y acute myeloid leukemia, drug repurposing, azacitidine, retinoic acid, pioglitazone, AML-ViVA, trial results
Maria E Goossens, Marc Van den Bulcke, Thierry Gevaert, Lydie Meheus, Dirk Verellen, Jean-Marc Cosset, and Guy Storme Author Is there any benefit to particles over photon radiotherapy? Journal Article Ecancermedicalscience 2019-12-09 Link No link Y Review, radiotherapy
Patrice Forget, Gauthier Bouche, Francois P. Duhoux, Pierre G. Coulie,Jan Decloedt, Alain Dekleermaker, Jean-Edouard Guillaume, Marc Ledent, Jean- Pascal Machiels, Véronique Mustin, Walter Swinnen, Aline van Maanen, Lionel Vander Essen, Jean-Christophe Verougstraete, Marc De Kock, Martine Berliere Author Intraoperative ketorolac in high-risk breast cancer patients. A prospective, randomized, placebo-controlled clinical trial Journal Article PLoS ONE 2019-12-04 Link Link Y trial results, breast cancer, ketorolac
Pan Pantziarka, Lydie Meheus Author Journal retractions in oncology: a bibliometric study Journal Article Future Medicine 2019-11-29 Link Link Y retracted articles, misinformation
N. André, A. Sterin, C. Solas, M.C. Le Deley, E. Tresch Bruneel, A. Probst, I. Aerts, C. Faure-Conter, A.I. Bertozzi, P. Chastagner, N. EntzWerlé, E. De Carli, G. Bouche, P. Leblond Author Phase I Study of Fluvastatin/Celecoxib Combination in Children with Relapsing or Refractory Low or High Grade Glioma - First Results Poster SIOP 2019 2019-11-26 No link Link Y trial results, paediatric glioma, Fluvabrex, drug repurposing
Daniel Heudobler, Christian Schulz, Jürgen R. Fischer, Peter Staib, Thomas Wehler, Thomas Südhoff, Thomas Schichtl, Jochen Wilke, Joachim Hahn, Florian Lüke, Martin Vogelhuber, Sebastian Klobuch, Tobias Pukrop, Wolfgang Herr, Swantje Held, Kristine Beckers, Gauthier Bouche, Albrecht Reichle Author Pioglitazone and clarithromycin combined with metronomic chemotherapy vs. nivolumab in patients with advanced non-small-cell lung cancer: Outcomes from a randomized phase II trial (ModuLung) Poster ESMO 2019 2019-09-28 No link Link Y non-small cell lung cancer, trial results, drug repurposing, ModuLung
Bishal Gyawali, Gauthier Bouche, Pan Pantziarka, Aaron S. Kesselheim, Ameet Sarpatwari Author Lung Cancer Survival Gains: Contributions of Academia and Industry Journal Article The Journal of Law, Medicine & Ethics 2019-09-27 Link Link Y lung cancer
An M. T. Van Nuffel, Caroline Boudousquié, Sandra Tuyaerts Author Approaches to Advance Cancer Vaccines to Clinical Utility Journal Article Frontiers in Immunology 2019-08-27 Link Link Y cancer vaccines, editorial
Pan Pantziarka, Nicolas André Author Drug Repurposing Journal Article Frontiers in Medicine 2019-07-03 Link Link Y drug repurposing, editorial
Sandra Tuyaerts, An M T Van Nuffel, Eline Naert, Peter A Van Dam, Peter Vuylsteke, Alex De Caluwé, Sandrine Aspeslagh, Piet Dirix, Lien Lippens, Emiel De Jaeghere, Frédéric Amant, Katrien Vandecasteele, Hannelore Denys Author PRIMMO Study Protocol: A Phase II Study Combining PD-1 Blockade, Radiation and Immunomodulation to Tackle Cervical and Uterine Cancer BMC Cancer Journal Article BMC Cancer 2019-05-28 Link Link Y Immune therapy, drug repurposing, PRIMMO, cervical cancer, uterine cancer, trial protocol
Pan Pantziarka, Gauthier Bouche Author Perioperative therapies - Using repurposed drugs to improve cancer surgery outcomes Journal Article The Cancer Journal 2019-04-10 Link Link Y Drug repurposing, perioperative therapy
A. Spini, G. Roberto, R. Gini, C. Bartolini, L. Bazzani, S. Donnini, S. Crispino, M. Ziche Author Evidence of β-blockers drug repurposing for the treatment of triple negative breast cancer: A systematic review Journal Article Neoplasma 2019-03-28 Link Link Y Triple negative breast cancer, drug repurposing, beta-blockers, review
Marie Christine Wulff Westergaard, Rikke Andersen, Chloé Chong, Julie Westerlin Kjeldsen, Magnus Pedersen, Christina Friese, Thomas Hasselager, Henrik Lajer, George Coukos, Michal Bassani-Sternberg, Marco Donia, Inge Marie Svane Acknowledged Tumour-reactive T Cell Subsets in the Microenvironment of Ovarian Cancer Journal Article British Journal of Cancer 2019-02-19 Link Link Y ovarian cancer, immune therapy
Tuyaerts, S., Rombauts, K., Everaert, T., Van Nuffel, AMT. and Amant, F. Author A Phase 2 Study to Assess the Immunomodulatory Capacity of a Lecithin-based Delivery System of Curcumin in Endometrial Cancer Journal Article Frontiers in Nutrition 2019-01-11 Link Link Y Endometrial cancer, trial results, curcumin
Pantziarka, P., Verbaanderd, C., Sukhatme, V., Capistrano, R., Crispino, S. Gyawali, B., Rooman, I., Van Nuffel, A. MT., Meheus, L., Sukhatme, V. P., & Bouche, G. Author ReDO_DB: the repurposing drugs in oncology database Journal Article Ecancermedicalscience 2018-12-06 Link Link Y database, drug repurposing
Forget Patrice, Bouche Gauthier, Duhoux Francois P., Coulie Pierre G., Decloedt Jan, Dekleermaker Alain, Guillaume Jean-Edouard, Ledent Marc, Machiels Jean-Pascal, Mustin Véronique, Swinnen Walter, Van Maanen Aline, Vander Essen Lionel, Verougstraete Jean-Christophe, De Kock Marc, Berliere Martine Author Intraoperative ketorolac in high-risk breast cancer patients with and without inflammation Poster SABCS 2018 2018-12-05 No link Link Y breast cancer, ketorolac, trial results, drug repurposing
Pan Pantziarka, Gauthier Bouche Author Drug Repurposing as a Source of Innovative Therapies in Chondrosarcoma Poster CTOS 2018 2018-11-15 No link Link Y chondrosarcoma, drug repurposing
Gauthier Bouche, Pan Pantziarka Author Multi-arm Trial in Localized Osteosarcoma: Moving from a Dream to Reality Poster CTOS 2018 2018-11-15 No link Link Y osteosarcoma, MAMS, PRESTO, trial design
Magnus Pedersen, Marie Christine Wulff Westergaard, Katy Milne, Morten Nielsen, Troels Holz Borch, Lars Grønlund Poulsen, Helle Westergren Hendel, Mia Kennedy, Gillian Briggs, Stacey Ledoux, Trine Jakobi Nøttrup, Pernille Andersen, Thomas Hasselager, Özcan Met, Brad H Nelson, Marco Donia, Inge Marie Svane. Acknowledged Adoptive Cell Therapy With Tumor-Infiltrating Lymphocytes in Patients With Metastatic Ovarian Cancer: A Pilot Study Journal Article OncoImmunology 2018-09-26 Link Link Y ovarian cancer, immune therapy, adoptive cell therapy, trial results
An M.T. Van Nuffel, Sandra Tuyaerts, Peter Van Dam, Peter Vuylsteke, Alex De Caluwé, Piet Dirix, Katrien Vandecasteele, Hannelore Denys Author Adding 5 immunomodulators to radio- and immunotherapy without further increasing financial toxicity Poster ImmunoRad 2018 2018-09-20 No link Link Y PRIMMO, interim trial results, drug repurposing, cervical cancer, endometrial cancer, immune therapy
Pantziarka, P. & Meheus, L. Author Omics-driven drug repurposing in rare cancers Journal Article Expert Opinion on Orphan Drugs 2018-07-24 Link Link N rare cancers, drug repurposing
Pantziarka, P., Pirmohamed, M., & Mirza, N. Author New uses for old drugs Journal Article BMJ 2018-06-26 Link Link N drug repurposing
Pantziarka, P., Bryan, B. A., Crispino, S., & Dickerson, E. B. Author Propranolol and breast cancer—a work in progress Journal Article Ecancermedicalscience 2018-06-18 Link Link Y breast cancer, drug repurposing, propranolol
Pan Pantziarka, Rica Capistrano I., Gauthier Bouche, Ilse Rooman Author Drug Repurposing as a Source of Innovative Therapies in Pancreatic Cancer Poster EPC 2018 2018-06-14 No link Link Y Pancreatic cancer, drug repurposing
Pantziarka, P., Bouche, G., & André, N. Author “Hard” Drug Repurposing for Precision Oncology: The Missing Link? Journal Article Frontiers in Pharmacology 2018-06-14 Link Link Y Drug repurposing, opinion article
Gauthier Bouche, Pan Pantziarka Author Drug Repurposing as a Source of Innovative Therapies in Osteosarcoma Poster ASCO18 2018-06-02 No link Link Y osteosarcoma, drug repurposing
Pantziarka, P., Sukhatme, V., Crispino, S., Bouche, G., Meheus, L., & Sukhatme, V. P. Author ReDO: selective PDE5 inhibitors as anti-cancer agents Journal Article Ecancermedicalscience 2018-04-11 Link Link Y drug repurposing, PDE5 inhibitors, ReDO project
Sergio Crispino, Lydie Meheus, Pan Pantziarka, Bishal Gyawali, Gauthier Bouche Author Repurposing non-cancer drugs for breast cancer? An emerging opportunity. Poster EBCC-11 2018-03-21 No link Link Y Breast cancer, drug repurposing
Bishal Gyawali, Pan Pantziarka, Sergio Crispino, Gauthier Bouche Author Does the oncology community have a rejection bias when it comes to repurposed drugs? Journal Article Ecancermedicalscience 2018-01-16 Link No link Y Drug repurposing, commentary
Verbaanderd, C., Maes, H., Schaaf, M. B., Sukhatme, V. P., Pantziarka, P., Sukhatme, V., Agostinis, P., & Bouche, G. Author ReDO: (hydroxy)chloroquine as anti-cancer agents Journal Article Ecancermedicalscience 2017-11-23 Link Link Y drug repurposing, hydroxychloroquine, chloroquine, ReDO project
Pantziarka, P., Bouche, G., Sullivan, R., Ilbawi, A.M., Dare, A.J., & Meheus, L. Author Perioperative therapies – Enhancing the impact of cancer surgery with repurposed drugs Journal Article European Journal of Surgical Oncology 2017-11-01 Link Link Y Perioperative therapy, drug repurposing
Bouche, G., Crisp, N., Gyawali, B., & André, N. Author Tap latent source of frugal cancer ideas. Journal Article Nature 2017-10-12 Link Link Y drug repurposing, letter
Verbaanderd, C., Meheus, L., Huys, I., & Pantziarka, P. Author Repurposing Drugs in Oncology: Next Steps Journal Article Trends in Cancer 2017-07-12 Link Link Y drug repurposing, financial and regulatory hurdles
Pantziarka, P. Author Scientific advice — is drug repurposing missing a trick? Journal Article Nature Reviews Clinical Oncology 2017-05-23 Link Link N drug repurposing, scientific advice
Pantziarka, P. Author On paranoid parents Journal Article Pediatric Blood & Cancer 2017-01-17 Link Link N ovarian cancer, sarcoma, parental paranoia
Pan Pantziarka, Lisa Hutchinson, Nicolas André, Sébastien Benzekry, Francesco Bertolini, Atanu Bhattacharjee, Shubhada Chiplunkar, Dan G. Duda, Vikram Gota, Sudeep Gupta, Amit Joshi, Sadhana Kannan, Robert Kerbel, Mark Kieran, Antonella Palazzo, Aparna Parikh, Eddy Pasquier, Vijay Patil, Kumar Prabhash, Yuval Shaked, Giselle Saulnier Sholler, Jaroslav Sterba, David J. Waxman, and Shripad Banavali Author Next generation metronomic chemotherapy-report from the Fifth Biennial International Metronomic and Anti-angiogenic Therapy Meeting, 6-8 May 2016, Mumbai Journal Article Ecancermedicalscience 2016-11-02 Link No link Y Meeting report, metronomic therapy
Pantziarka, P., Bouche, G., Sukhatme, V., Meheus, L., Rooman, I., & Sukhatme, V. P. Author ReDO: propranolol as an anti-cancer agent Journal Article Ecancermedicalscience 2016-10-12 Link Link Y propranolol, drug repurposing, ReDO project
Pantziarka, P., Sukhatme, V., Bouche, G., Meheus, L., & Sukhatme, V. P. Author ReDO: diclofenac as an anti-cancer agent Journal Article Ecancermedicalscience 2016-01-11 Link Link Y drug repurposing, diclofenac, ReDO project
Bertolini, F., Sukhatme, V.P., & Bouche, G. Author Patient and health systems opportunities Journal Article Nature Reviews Clinical Oncology 2015-10-20 Link Link N drug repurposing, health economics
Yolanda Augustin, Sanjeev Krishna, Devinder Kumar, Pan Pantziarka Author The wisdom of crowds and the repurposing of artesunate as an anticancer drug Journal Article Ecancermedicalscience 2015-10-13 Link No link Y Drug repurposing, artesunate
Vidula Sukhatme, Gauthier Bouche, Lydie Meheus, Vikas P Sukhatme and Pan Pantziark Author ReDO: nitroglycerin as an anti-cancer agent Journal Article Ecancermedicalscience 2015-08-27 Link Link Y Nitroglycerin, drug repurposing, ReDO project
Dinesh Chandra, Arthee Jahangir, Francois Cornelis, Klara Rombauts, Lydie Meheus, Cheryl L Jorcyk, Claudia Gravekamp Author Therapeutic effect of Cryoablation and Meriva in Breast Cancer Journal Article OncoImmunology 2015-05-29 Link Link Y triple-negative breast cancer, cryoablation, Meriva, preclinical
Pan Pantziarka, Vidula Sukhatme, Gauthier Bouche, Lydie Meheus and Vikas P Sukhatme Author ReDO: itraconazole as an anti-cancer agent Journal Article Ecancermedicalscience 2015-04-15 Link Link Y Itraconazole, drug repurposing, ReDO proejct
Rica Capistrano Author Phytochemical, Analytical and Preclinical Investigations on Plant Extracts as Potential Antitumoural Therapy Thesis 2015-03-18 No link Link Y Analytical method development, Preclinical studies, Phytochemical analysis, Plant extracts, Pancreatic cancer
An MT Van Nuffel, Vidula Sukhatme, Pan Pantziarka, Lydie Meheus, Vikas P Sukhatme and Gauthier Bouche Author ReDO: clarithromycin as an anti-cancer agent Journal Article Ecancermedicalscience 2015-02-24 Link Link Y Clarithromycin, drug repurposing, ReDO project
Pantziarka, P., Bouche, G., Meheus, L., Sukhatme, V., & Sukhatme, V.P. Author Repurposing in your medicine cabinet Journal Article Future Oncology 2015-01-16 Link Link Y drug repurposing, health economics
Pantziarka, P., Bouche, G., Meheus, L., Sukhatme, V., & Sukhatme, V. P. Author ReDO: cimetidine as an anti-cancer agent Journal Article Ecancermedicalscience 2014-11-26 Link Link Y Cimetidine, drug repurposing, ReDO project
Gauthier Bouche, Nicolas André, Shripad Banavali, Frank Berthold, Alfredo Berruti, Guido Bocci, Giovanni Brandi, Ugo Cavallaro, Saviero Cinieri, Marco Colleoni, Giuseppe Curigliano, Teresa Di Desidero, Alexandru Eniu, Nicola Fazio, Robert Kerbel, Lisa Hutchinson, Urszula Ledzewicz, Elisabetta Munzone, Eddy Pasquier, O Graciela Scharovsky, Yuval Shaked, Jaroslav Stěrba, Martin Villalba, Francesco Bertolini Author Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24-25 June 2014, Milan Journal Article Ecancermedicalscience 2014-09-09 Link No link Y Meeting report, metronomic therapy
Ana Ugarte, Gauthier Bouche, Lydie Meheus Author Inconsistencies and questionable reliability of the publication "immunotherapy of metastatic colorectal cancer with vitamin D-binding protein-derived macrophages-activating, GcMAF" by Yamamoto et al Journal Article Cancer Immunology, Immunotherapy 2014-07-24 Link No link Y GcMAF
Pantziarka, P., Bouche, G., Meheus, L., Sukhatme, V., & Sukhatme, V. P. Author ReDO: mebendazole as an anti-cancer agent Journal Article Ecancermedicalscience 2014-07-10 Link No link Y Mebendazole, drug repurposing, ReDO project
Pantziarka, P., Bouche, G., Meheus, L., Sukhatme, V., & Sukhatme, V. P. Author The Repurposing Drugs in Oncology (ReDO) Project Journal Article Ecancermedicalscience 2014-07-10 Link Link Y drug repurposing, ReDO project
Pan Pantziarka, Linda Cairns Author Recycling existing drugs for cancer therapy: delivering low cost cancer care Journal Article Ecancermedicalscience 2014-07-10 Link No link Y Drug repurposing, health economics
Werbrouck, J., Bouche, G., de Jonge, E., Jacomen, G., D'Hondt, V., Denys, H., Van Limbergen, E., Vandermeersch, B., De Schutter, H., Van Eycken, E., Goffin, F., & Amant, F. Author Evaluation of the quality of the management of cancer of the corpus uteri--selection of relevant quality indicators and implementation in Belgium. Journal Article Gynecologic Oncology 2013-12-01 Link Link N EFFECT, uterine cancer
Patrice Forget, Martine Berlière, Aline van Maanen, Francois P Duhoux, Jean-Pascal Machiels, Pierre G Coulie, Gauthier Bouche, Marc De Kock, Ketorolac in Breast Cancer trial (KBCtrial) group Author Perioperative ketorolac in high risk breast cancer patients. Rationale, feasibility and methodology of a prospective randomized placebo-controlled trial Journal Article Medical Hypotheses 2013-08-09 Link No link N Ketorolac, trial protocol, breast cancer, drug repurposing